Steph Houghton has sustained an injury to her right knee and will be undergoing surgery this week to treat it.
Izzy Christiansen and Jordan Nobbs have also withdrawn from the England squad due to minor thigh and foot injuries respectively.
Both players will return to their clubs and play no part in Friday’s FIFA Women’s World Cup qualifier in Russia.
Lauren Bruton [Reading] and Lucy Staniforth [Sunderland] will now join Phil Neville’s 20-player squad for the trip to Moscow – their first senior call-ups.
Arsenal’s Leah Williamson is drafted into the 20-player squad as cover for the England skipper.
Defender Gabby George (Everton), Alex Greenwood (Liverpool), and Aoife Mannion (Birmingham City) are all training with Phil Neville’s squad at St. George’s Park this week.
Goalkeepers: Karen Bardsley Mary Earps Carly Telford
Defenders: Hannah Blundell Millie Bright Lucy Bronze Rachel Daly Leah Williamson Abbie McManus
Midfielders: Fran Kirby Jill Scott Keira Walsh Lauren Bruton Lucy Staniforth
Forwards: Toni Duggan Melissa Lawley Beth Mead Nikita Parris Jodie Taylor Ellen White
Courtesy of the FA